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Salicortin

CAT: 0804-HY-123503-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-123503-01Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity[1].
CAS Number
1887055-63-1
UNSPSC
12352005
Target
JNK; NF-κB
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/salicortin.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC=CC=C2COC([C@]3(O)C=CCCC3=O)=O
Molecular Formula
C20H24O10
Molecular Weight
424.40
References & Citations
[1]Nie S, et al. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Biochem Biophys Res Commun. 2016 Jan 29;470 (1) :61-67.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
JNK; NF-κB

Alternative Products

CatalogName
AR-S09872-01Salicortin
XS170492-01Salicortin - Populus sp. (Poplar)

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