FR 64822

• Description:

  FR 64822 is a dopamine D2 receptor agonist that can induce antinociceptive activity in rats and mice by indirectly stimulating dopamine D2 receptors. FR 64822 can promote penile erection in juvenile rats and improve amnesia in rats induced by scopolamine during passive avoidance tasks[1].

• UNSPSC:

  12352005

• Target:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/fr-64822.html

• Smiles:

  O=C (NN1CC=CCC1) NC2=CC=NC=C2

• Molecular Formula:

  C11H14N4O

• Molecular Weight:

  218.26

• References & Citations:

  [1]Ohkubo Y, et al. Involvement of dopamine in the mechanism of action of FR64822, a novel non-opioid antinociceptive compound. Eur J Pharmacol. 1991 Nov 5;204 (2) :121-5. |[2]Maeda N, et al. A screening concept based on a hypothesis led to the development of a putative cognitive enhancer that stimulates penile erection. Jpn J Pharmacol. 1994 Mar;64 (3) :147-53.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  D2 Receptor

• CAS Number:

  102671-35-2