Itaconic acid

CAT: 0804-HY-Y0520-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-Y0520-01Size:100 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect[1][2][4][5].
CAS Number
[97-65-4]
Product Name Alternative
Methylenesuccinic acid
UNSPSC
12352211
Hazard Statement
H318, H402
Target
Endogenous Metabolite; Ferroptosis
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/propylenedicarboxylic-acid.html
Purity
99.98
Solubility
H2O : 27.78 mg/mL (ultrasonic)
Smiles
O=C(O)C(CC(O)=O)=C
Molecular Formula
C5H6O4
Molecular Weight
130.10
Precautions
H318, H402
References & Citations
[1]Weiss JM, et, al. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. J Clin Invest. 2018 Aug 31;128 (9) :3794-3805.|[2]Zhao M, et, al. Itaconic acid production in microorganisms. Biotechnol Lett. 2018 Mar;40 (3) :455-464.|[3]Qu C, et al. Itaconic acid induces ferroptosis by activating ferritinophagy. Biochem Biophys Res Commun. 2021 Oct 25;583:56-62. |[4]Zhu X, et al. Itaconic acid exerts anti-inflammatory and antibacterial effects via promoting pentose phosphate pathway to produce ROS. Sci Rep. 2021 Sep 13;11 (1) :18173.|[5]Umbrasas D, et al. Effects of itaconic acid on neuronal viability and brain mitochondrial functions. J Bioenerg Biomembr. 2021 Oct;53 (5) :499-511.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

Related Products

CatalogName
HY-140589Acid-PEG4-S-PEG4-acid
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-108398AMead acid
HY-N13739-01Taraxinic acid
HY-N13062Morusimic acid A
HY-N1412ADicaffeoylquininic acid
HY-N13672Macedonic acid

Alternative Products

CatalogName
MBS5751321Itaconic acid
sc-495554AItaconic acid-13C5
TRC-I931006-250MGitaconic Acid-d4

Popular Products