Diazoketone methotrexate

Diazoketone methotrexate

• CAS Number: 82972-54-1
• UNSPSC Description: Diazoketone methotrexate, an analog of methotrexate, is an antitumor agent. Diazoketone methotrexate inhibits cell growth and inhibits synthesis of thymidylate[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/diazoketone-methotrexate.html
• Smiles: NC1=NC(N)=NC2=NC=C(CN(C3=CC=C(C(N[C@H](C(O)=O)CCC(C=[N+]=[N-])=O)=O)C=C3)C)N=C12
• Molecular Weight: 478.46
• References & Citations: [1]Gangjee A, et al. Diazoketone and chloromethylketone analogs of methotrexate as potential antitumor agents. J Pharm Sci. 1982 Jun;71(6):717-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported