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Ammonium chloride-d4

CAT: 0804-HY-Y1269AS-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y1269AS-01Size:1 g
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Description
Ammonium chloride-d4 is the deuterium labeled Ammonium chloride. Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor[1][2][3].
CAS Number
12015-14-4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.9
Solubility
10 mM in DMSO
Smiles
ClN([2H])([2H])([2H])[2H]
Molecular Formula
ClD4N
Molecular Weight
57.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Huang X, et al. NH4Cl treatment prevents doxorubicin-induced myocardial dysfunction in vivo. Life Sci. 2019;227:94-100. |[2]Canning WM, Fields BN. Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science. 1983;219 (4587) :987-988. |[3]Yu C, et al. Lysosome dysfunction enhances oxidative stress-induced apoptosis through ubiquitinated protein accumulation in Hela cells. Anat Rec (Hoboken) . 2013 Jan;296 (1) :31-9.
Shipping Conditions
Room Temperature
Storage Conditions
RT, sealed storage, away from moisture and light
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Chemical Information

Ammonium-d4 chloride
CAS Number12015-14-4
PubChem CID16211389
IUPAC Nametetradeuterioazanium chloride
Molecular FormulaClH4N
Molecular Weight57.51
Topological Polar Surface Area1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Heavy Atom Count2
Formal Charge0
Complexity0
SMILES
[2H][N+]([2H])([2H])[2H].[Cl-]
InChI
InChI=1S/ClH.H3N/h1H;1H3/i/hD4
InChIKey
NLXLAEXVIDQMFP-JBISRTOLSA-N
Chemical Structure
2D Structure
2D structure of Ammonium-d4 chloride
CAS: 12015-14-4
CID: 16211389
Formula: ClH4N
MW: 57.51
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight57.51
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass57.0283338
Monoisotopic Mass57.0283338
Topological Polar Surface Area1 Ų
Heavy Atom Count2
Formal Charge0
Complexity0
Isotope Atom Count4
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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