Products for Research Use Only
RegisterLogin

18-Crown-6-ether

CAT: 0804-HY-D0180Size: 100 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-D0180Size:100 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
18-Crown-6-ether is a type of crown ether compound and a specific structure dissociating agent. 18-Crown-6-ether can compete with K+ for binding to G-quadruplexes, disrupting their stable structure to regulate the functions of related systems. 18-Crown-6-ether combines with K+ and other metal ions to achieve precise ion transmembrane transport. 18-Crown-6-ether can act as an "susceptibility substrate" for the multi-drug efflux pump EmrE (a bacterial multidrug resistance transporter), ultimately inhibiting bacterial growth. 18-Crown-6-ether can be used in microcapsule controlled release and the research on developing antibacterial enhancers[1][2][3].
CAS Number
17455-13-9
Product Name Alternative
18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane
UNSPSC
12352200
Hazard Statement
H302
Target
Bacterial
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/18-crown-6-ether.html
Purity
99.77
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O1CCOCCOCCOCCOCCOCC1
Molecular Formula
C12H24O6
Molecular Weight
264.32
Precautions
H302
References & Citations
[1]Lilienthal S, et al. Single and Bilayer Polyacrylamide Hydrogel-Based Microcapsules for the Triggered Release of Loads, Logic Gate Operations, and Intercommunication between Microcapsules. ACS Appl Mater Interfaces. 2020 Jul 15;12 (28) :31124-31136.|[2]Fong C W. Physiology of ionophore transport of potassium and sodium ions across cell membranes: Valinomycin and 18-Crown-6 Ether. International Journal of Computational Biology and Drug Design, 2016, 9 (3) : 228-246.|[3]Brousseau M, et al. 18-Crown-6-ether Utilizes Distinct Allosteric Interactions to Uncouple Transport by the Multidrug Efflux Pump EmrE. Biochemistry. 2025 Sep 16;64 (18) :3956-3970.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-40309Dibenzo-18-crown-6
HY-W073183Dibenzo-24-crown-8-ether
HY-W008585Benzo-15-crown-5-ether
HY-W008948-01Bis (L-tartaric acid) 18-crown-6
HY-W127846-014',4'' (5'') -Di-tert-butyldibenzo-18-crown-6
HY-W127624APEG 18 cetostearyl ether
HY-135584Raloxifene 6-Monomethyl Ether
HY-W016693-0112-Crown-4
HY-W007451-0115-Crown-5
HY-112418-01CDK4/6-IN-18

Alternative Products

CatalogName
27395735-25g18-Crown-6-Ether
50301618‐CROWN‐6‐ETHER
1032250 5Crown Ether / Dibenzo-18-Crown-6 for Synthesis (Dibenzo 18-Crown-6)
OR72919-01Dicyclohexano-18-crown 6-ether
OR10927Decyl-18-crown-6-ether
GTR19248029-01Dicyclohexano-18-crown-6-ether
1032230 2518-Crown-6-Ether For Synthesis
TSH-00052-01Benzo-18-crown-6-ether
504003DIBENZO 18‐CROWN‐6‐ETHER
FC62074-014'-Carboxybenzo-18-crown 6-ether

Popular Products