Rapacuronium bromide

• Description :

  Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR) [1].

• Product Name Alternative :

  Org 9487

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H331

• Target :

  MAChR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/RAPACURONIUM_BROMIDE.html

• Purity :

  98.0

• Solubility :

  DMSO : ≥ 125 mg/mL

• Smiles :

  C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])C[C@H]([N+]5(CC=C)CCCCC5)[C@@H]4OC(CC)=O)([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C1.[Br-]

• Molecular Formula :

  C37H61BrN2O4

• Molecular Weight :

  677.80

• Precautions :

  H302, H312, H331

• References & Citations :

  [1]Jakubík J, et al. Divergence of allosteric effects of Rapacuronium on binding and function of muscarinic receptors. BMC Pharmacol. 2009 Dec 28;9:15.|[2]Vizi ES, et al. A new short-acting non-depolarizing muscle relaxant (SZ1677) without cardiovascular side-effects. Acta Anaesthesiol Scand. 2003 Mar;47 (3) :291-300.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [156137-99-4]