4-Methylumbelliferyl β-D-Glucopyranoside

4-Methylumbelliferyl β-D-Glucopyranoside

• CAS Number: 18997-57-4
• UNSPSC Description: 4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity[1]. 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively[2].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-methylumbelliferyl-β-d-glucopyranoside.html
• Purity: 99.83
• Solubility: DMF : 50 mg/mL (ultrasonic)|DMSO : 100 mg/mL (ultrasonic)
• Smiles: OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC2=CC=C3C(C)=CC(OC3=C2)=O)O)O)O
• Molecular Weight: 338.31
• References & Citations: [1]Smitka CM,et al. Rapid fluorogenic assay for differentiation of the Candida parapsilosis group from other Candida spp. J Clin Microbiol. 1989;27(1):203-206.|[2]Oftedal L, et al. Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid. Sci Rep. 2020;10(1):22098. Published 2020 Dec 16.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported