4-Methylumbelliferyl-α-D-Glucopyranoside
CAT:
804-HY-137873-06
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

4-Methylumbelliferyl-α-D-Glucopyranoside
- CAS Number: 17833-43-1
- UNSPSC Description: 4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. 4-Methylumbelliferyl-α-D-Glucopyranoside can be used as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Target Antigen: Fluorescent Dye; Glycosidase
- Type: Dye Reagents
- Related Pathways: Metabolic Enzyme/Protease;Others
- Field of Research: others
- Assay Protocol: https://www.medchemexpress.com/4-methylumbelliferyl-α-d-glucopyranoside.html
- Smiles: O=C1C=C(C)C2=CC=C(O[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C=C2O1
- Molecular Weight: 338.31
- References & Citations: [1]Zhi, et al. Fluorescent properties of hymecromone and fluorimetric analysis of hymecromone in compound dantong capsule. J. Spectrosc. 147128 (2013).
- Shipping Conditions: Room Temperature