Products for Research Use Only
RegisterLogin

Elacestrant-d10

CAT: 0804-HY-19822S2Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19822S2Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Elacestrant-d10 is the deuterium labeled of Elacestrant. Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also inhibits growth of ER+ breast cancer cell lines in vitro and in vivo[1][2].
Product Name Alternative
RAD1901-d10
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
OC1=C(C([2H])=C2C[C@@H](CCC2=C1[2H])C3=C(C([2H])=C(C([2H])=C3N(CC4=C(C([2H])=C(C([2H])=C4[2H])CCNCC)[2H])CC)OC)[2H])[2H]
Molecular Formula
C30H28D10N2O2
Molecular Weight
468.70
References & Citations
[1]Garner F, et al. RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26 (9) :948-56.|[2]Bihani T, et al. Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models. Clin Cancer Res. 2017 Aug 15;23 (16) :4793-4804.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-19822-01Elacestrant
HY-19822S3Elacestrant-d6
HY-19822SElacestrant-d4
HY-19822A-01Elacestrant (dihydrochloride)
HY-19822S1Elacestrant-d4-1
HY-19822D-01Elacestrant (S enantiomer)
HY-19822BElacestrant (S enantiomer dihydrochloride)
HY-P0009S1Cetrorelix-d10
HY-13673SGoserelin-d10
HY-W744750TDHL-d10

Alternative Products

CatalogName
E7121-1mgElacestrant
CS-O-63663Elacestrant-d4
A12244-25Elacestrant 25mg
A12244-1Elacestrant 1mg
GTR19176146-01Elacestrant dihydrochloride
A12244-100Elacestrant 100mg
A12244-5Elacestrant 5mg
TRC-E407311-10MGElacestrant-d5

Popular Products