3-Hydroxyxanthone

• Description:

  3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) . 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].

• Product Name Alternative:

  3-Hydroxy-xanthen-9-one

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319

• Target:

  Integrin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/3-hydroxyxanthone.html

• Purity:

  99.68

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C1C2=C(OC3=C1C=CC=C3)C=C(O)C=C2

• Molecular Formula:

  C13H8O3

• Molecular Weight:

  212.20

• Precautions:

  H302, H315, H319

• References & Citations:

  [1]Madan B, et al. Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) . Bioorg Med Chem. 2002 Nov;10 (11) :3431-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3722-51-8