(2R,4R)-UCB7362 (hydrochloride)

(2R,4R)-UCB7362 (hydrochloride)

• CAS Number: 2610631-18-8
• UNSPSC Description: (2R,4R)-UCB7362 hydrochloride is the (2R,4R) isomer of UCB7362, an inhibitor of plasma proteinase X (PMX) with antimalarial activity[1].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: infection
• Assay Protocol: https://www.medchemexpress.com/2r-4r-ucb7362-hydrochloride.html
• Smiles: O=C(NC1=CC=CC([C@@](CC(N2[C@H]3C[C@@H](C)OCC3)=O)(C)NC2=N)=C1Cl)C4=CC=CC(C#N)=C4.Cl.[x]
• Molecular Weight: 479.96(free base)
• References & Citations: [1]Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 27;65(20):14121-14143.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported