Diallyl Trisulfide

• Description :

  Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer[1][2][3][4].

• Product Name Alternative :

  2-Amino-4-phosphonobutyric acid

• UNSPSC :

  12352100

• Hazard Statement :

  H301

• Target :

  Apoptosis; Bcl-2 Family; Fungal; Influenza Virus; Interleukin Related; Reactive Oxygen Species (ROS) ; SOD

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/diallyl-trisulfide.html

• Purity :

  99.9

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  C=CCSSSCC=C

• Molecular Formula :

  C6H10S3

• Molecular Weight :

  178.34

• Precautions :

  H301

• References & Citations :

  [1]Pu Liu, et al. Diallyl trisulfide (DATS) effectively induced apoptosis of postharvest diseasePenicillium expansum of citrus. Annals of Microbiology. December 2009, Volume 59, Issue 4, pp 675-679.|[2]Li W, et al. Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo. Acta Biochim Biophys Sin (Shanghai) . 2012 Jul;44 (7) :577-83. |[3]Zhang F, et al. Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice. Int Immunopharmacol. 2015 Dec;29 (2) :326-333.|[4]Ming L, et al. Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo. Virol J. 2021 Aug 19;18 (1) :171.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  IL-6; IL-8

• CAS Number :

  [2050-87-5]