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Diallyl disulfide

CAT: 0804-HY-W015635-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W015635-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC50 of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities[1][2][3][4].
CAS Number
2179-57-9
UNSPSC
12352100
Hazard Statement
H227, H301, H315, H319, H335
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/diallyl-disulfide.html
Purity
99.8
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CCSSCC=C
Molecular Formula
C6H10S2
Molecular Weight
146.27
Precautions
H227, H301, H315, H319, H335
References & Citations
[1]Gupta N, et al. Garlic and garlic-derived compounds inhibit human squalene monooxygenase. J Nutr. 2001;131 (6) :1662-1667. |[2]You-Sheng Huang, et al. Diallyl disulfide inhibits the proliferation of HT-29 human colon cancer cells by inducing differentially expressed genes. Mol Med Rep. 2011 May-Jun;4 (3) :553-9.|[3]Xiaoyou Wei, et al. Acute Diallyl Disulfide Administration Prevents and Reveres Lipopolysaccharide-Induced Depression-Like Behaviors in Mice via Regulating Neuroinflammation and Oxido-Nitrosative Stress. Inflammation. 2021 Aug;44 (4) :1381-1395.|[4]Aline de Oliveira Pontes Cardoso, et al. Diallyl disulfide prevents cigarette smoke-induced emphysema in mice. Pulm Pharmacol Ther. 2021 Aug:69:102053.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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