Dilmapimod (tosylate)

• UNSPSC Description:

  Dilmapimod tosylate is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.

• Target Antigen:

  Autophagy; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  Autophagy;MAPK/ERK Pathway

• Field of Research:

  Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dilmapimod-tosylate.html

• Smiles:

  O=S(O)(C1=CC=C(C=C1)C)=O.O=C2C=CC3=C(C4=CC=C(F)C=C4C)N=C(NC(CO)CO)N=C3N2C5=C(F)C=CC=C5F

• Molecular Weight:

  628.62

• References & Citations:

  [1]Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  937169-00-1