Clathrin-IN-4
CAT:
804-HY-152218-06
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Clathrin-IN-4
- CAS Number: 762242-59-1
- UNSPSC Description: Clathrin-IN-4 (compound 8b), a Wiskostatin (HY-12534) analogue, is a potent inhibitor of clathrin mediated endocytosis with an IC50 of 2.1 μM. Clathrin-IN-4 is a dynamin I GTPase activity inhibitor with an IC50 of 9.1 μM[1].
- Target Antigen: Dynamin
- Type: Reference compound
- Related Pathways: Cytoskeleton
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/clathrin-in-4.html
- Solubility: DMSO : 90 mg/mL (ultrasonic)
- Smiles: CN(C[C@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
- Molecular Weight: 426.15
- References & Citations: [1]Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported