Clathrin-IN-2
CAT:
804-HY-152217
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Clathrin-IN-2
- CAS Number: 2650733-69-8
- UNSPSC Description: Clathrin-IN-2 is potent inhibitor of clathrin mediated endocytosis (CME) with an IC50 value of 2.3 μM. Clathrin-IN-2 also has inhibitiory for dyn I GTPase with an IC50 value of 7.7 μM[1].
- Target Antigen: Dynamin
- Type: Reference compound
- Related Pathways: Cytoskeleton
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Metabolic Disease; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/clathrin-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: CN(C[C@@H](CN1C2=CC=C(C=C2C3=CC(Br)=CC=C31)Br)O)C
- Molecular Weight: 426.15
- References & Citations: [1]Peter J Cossar, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported