DDR1 (Phospho Tyr796) rabbit pAb

• Background:

  Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., domain:The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates., function:May be involved in cell-cell interactions and recognition., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily., similarity:Contains 1 F5/8 type C domain., similarity:Contains 1 protein kinase domain., tissue specificity:Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.

• Description:

  Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. Domain: The Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates. function: May be involved in cell-cell interactions and recognition. similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. similarity: Contains 1 F5/8 type C domain. similarity: Contains 1 protein kinase domain. tissue specificity: Expressed at low levels in most adult tissues and is highest in the brain and lung. Abundant in breast carcinoma cell lines.

• Synonyms:

  Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1;EC 2.7.10.1;CD167 antigen-like family member A;Cell adhesion kinase;Discoidin receptor tyrosine kinase;HGK2;Mammary carcinoma kinase 10;MCK-10;Protein-tyrosine kinase 3A;Protein-tyrosine kinase RTK-6;TRK E;Tyrosine kinase DDR;Tyrosine-protein kinase CAK;CD antigen CD167a)

• Gene ID:

  780

• UniProt:

  Q08345

• Cellular Locus:

  [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human DDR1 (Phospho Tyr796)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-2000 ELISA 1:5000-20000

• Molecular Weight:

  100kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  100 kD

• Subcellular Location:

  [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.

• Other Product Names:

  Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1; EC 2.7.10.1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; CD antigen CD167a)

• Gene ID (Human):

  780

• SwissProt (Human):

  Q08345