AIF Blocking Peptide

• Description:

  AIF Blocking Peptide_x000D_ Catalog number: B2017234_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 200 µg_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: Apoptosis-Inducing Factor, Programmed Cell Death Protein 8_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, Neifert S, Qian J, Andrabi SA, Blackshaw S, Zhu H, Song H, Ming GL, Dawson VL, Dawson TM. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1 Science. 2016 Oct 7;354(6308):aad6872._x000D_ 2: Chelko SP, Keceli G, Carpi A, Doti N, Agrimi J, Asimaki A, Beti CB, Miyamoto M, Amat-Codina N, Bedja D, Wei AC, Murray B, Tichnell C, Kwon C, Calkins H, James CA, O'Rourke B, Halushka MK, Melloni E, Saffitz JE, Judge DP, Ruvo M, Kitsis RN, Andersen P, Di Lisa F, Paolocci N. Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy Sci Transl Med. 2021 Feb 17;13(581):eabf0891._x000D_ 3: Modjtahedi N, Giordanetto F, Madeo F, Kroemer G. Apoptosis-inducing factor: vital and lethal Trends Cell Biol. 2006 May;16(5):264-72._x000D_ 4: Dawson VL, Dawson TM. Deadly conversations: nuclear-mitochondrial cross-talk J Bioenerg Biomembr. 2004 Aug;36(4):287-94._x000D_ 5: Rodriguez J, Xie C, Li T, Sun Y, Wang Y, Xu Y, Li K, Zhang S, Zhou K, Wang Y, Mallard C, Hagberg H, Doti N, Wang X, Zhu C. Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia Neuropharmacology. 2020 Jul;171:108088._x000D_ 6: Zhang Y, Zhang C, Li J, Jiang M, Guo S, Yang G, Zhang L, Wang F, Yi S, Wang J, Fu Y, Zhang Y. Inhibition of AKT induces p53/SIRT6/PARP1-dependent parthanatos to suppress tumor growth Cell Commun Signal. 2022 Jun 17;20(1):93._x000D_ 7: Monti A, Sturlese M, Caporale A, Roger JA, Mascanzoni F, Ruvo M, Doti N. Design, synthesis, structural analysis and biochemical studies of stapled AIF(370-394) analogues as ligand of CypA Biochim Biophys Acta Gen Subj. 2020 Dec;1864(12):129717._x000D_ 8: Greenwald SH, Pierce EA. Parthanatos as a Cell Death Pathway Underlying Retinal Disease Adv Exp Med Biol. 2019;1185:323-327._x000D_ 9: Song Y, Fan Z, Bai X, Liu W, Han Y, Xu L, Wang M, Li J, Zheng Q, Zhang D, Wang H. PARP-1-modulated AIF translocation is involved in streptomycin-induced cochlear hair cell death Acta Otolaryngol. 2016 Jun;136(6):545-50._x000D_ 10: Galluzzi L, Morselli E, Kepp O, Kroemer G. Targeting post-mitochondrial effectors of apoptosis for neuroprotection Biochim Biophys Acta. 2009 May;1787(5):402-13. _x000D_ _x000D_ Products Related to AIF Blocking Peptide can be found at Proteins

• Short Description:

  Catalog Number: B2017234 (200 µg)_x000D_ AIF Blocking Peptide is a high quality peptide used in scientific research to inhibit the activity of Apoptosis-Inducing Factor (AIF). AIF is a protein that plays a crucial role in the process of programmed cell death (apoptosis) and is also involved in other cellular processes such as mitochondrial energy metabolism. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  35

• Length:

  8

• Width:

  8

• Height :

  8