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Phosphoglucomutase 5 Antibody / PGM5 / Aciculin

CAT: 0800-V9692SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V9692SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q15124
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the Phosphoglucomutase 5 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
PGM5/3552
Applications
ELISA, WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Phosphoglucomutase 5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Phosphoglucomutase 5 antibody is available for research use only.
Storage Conditions
Aliquot the Phosphoglucomutase 5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Phosphoglucomutase 5 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human heart tissue lysate using Phosphoglucomutase 5 antibody (clone PGM5/3552) . Predicted molecular weight ~62 kDa.

UniProtKB · Q15124

Phosphoglucomutase-like protein 5

PGM5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15124
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PGM5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B1AM46, B4DLQ6, Q5VYV3, Q8N527, Q9UDH4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell junctionCell membraneCytoplasmCytoskeletonMembrane

PTM

Phosphoprotein

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