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IGFBP3 Antibody

CAT: 0800-V9556-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V9556-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P17936
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length IGFBP3 protein was used as the immunogen for the IGFBP3 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
IGFBP3/3517
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the IGFBP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IGFBP3 antibody is available for research use only.
Storage Conditions
Aliquot the IGFBP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the IGFBP3 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using IGFBP3 antibody (clone IGFBP3/3517) . These results demonstrate the foremost specificity of the IGFBP3/3517 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

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