AR-V7 Recombinant Antibody / Androgen Receptor

AR-V7 Recombinant Antibody / Androgen Receptor

• Description: AR V7 belongs to the nuclear hormone receptor family. It contains the nuclear receptor DNA binding domain. Steroid hormone receptors are ligand-activated transcription factors that regulate the expression of eukaryotic genes affecting cell proliferation and differentiation in target tissues. The activity of transcription factors is regulated by binding co-activators and co-repressors. This target is a splice variant of the androgen receptor that lacks the C-terminal androgen-binding site. AR-V7 plays an important role in the occurrence, development and drug resistance of prostate cancer.
• CAS Number: 9000-83-3
• UniProt: P10275
• Host: Rabbit
• Immunogen: A recombinant fragment (within amino acids 600-920) of human AR protein (AR-V7 specific) was used as the immunogen for the recombinant Androgen Receptor V7 antibody.
• Clonality: Monoclonal
• Isotype: IgG κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the recombinant Androgen Receptor V7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This recombinant Androgen Receptor V7 antibody is available for research use only.