POLR2B Antibody / DNA-directed RNA polymerase II subunit RPB2

POLR2B Antibody / DNA-directed RNA polymerase II subunit RPB2

• Description: DNA-directed RNA polymerase II subunit RPB2 is an enzyme that in humans is encoded by the POLR2B gene. This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.
• CAS Number: 9007-83-4
• UniProt: P30876
• Host: Rabbit
• Immunogen: An E.coli-derived human recombinant protein (E49-Q1145) was used as the immunogen for the RPB2 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IF, FACS, ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the RPB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This RPB2 antibody is available for research use only.