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Nardilysin Antibody / NRDC / NRD1

CAT: 0800-RQ8325Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8325Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
O43847
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (K427-R967) was used as the immunogen for the Nardilysin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Nardilysin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Nardilysin antibody is available for research use only.
Storage Conditions
After reconstitution, the Nardilysin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Nardilysin antibody should be determined by the researcher.
Image Legend
Flow cytometry testing of fixed and permeabilized human MCF7 cells with Nardilysin antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= Nardilysin antibody.

UniProtKB · O43847

Nardilysin

NRDC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43847
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NRDC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.24.61
Processing
Precursor
Secondary accessions
A6NI41, O15241, O15242, Q5VUL0, Q96HB2, Q9NU57
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell projectionMitochondrion

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

Signal

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