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Thbd Antibody / Thrombomodulin

CAT: 0800-RQ8267Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8267Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. [UniProt]
CAS Number
9000-83-3
Specifications
Western blot: 1:500-1:2000
UniProt
P15306
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide derived from human Thrombomodulin was used as the immunogen for the Thbd antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28T28
Type
Recombinant
Applications
WB
Purity
Affinity chromatography
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the Thbd antibody at -20oC.
Limitations
This Thbd antibody is available for research use only.
Storage Conditions
Store the Thbd antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Thbd antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse lung tissue lysate with Thbd antibody. Expected molecular weight ~60/100 kDa (unmodified/glycosylated) .

UniProtKB · P15306

Thrombomodulin

TRBM_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P15306
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Thbd
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
TM
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Biological process

Blood coagulationHemostasis

PTM

Disulfide bondGlycoproteinProteoglycan

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Molecular function

Receptor

Technical term

Reference proteome

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