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Simtuzumab Biosimilar - Research Grade

CAT: 1148-ICH5068-50mgSize: 50 mgDry Ice: NoHazardous: No
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CAT#:1148-ICH5068-50mgSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Specifications
Detects human LOXL2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Simtuzumab.
UniProt
Q9Y4K0
Species Reactivity
Human
Target
LOXL2
Isotype
IgG4
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
https://ichor.bio/product/bulk-human-igg4-isotype-control-ib4-ich2257/

UniProtKB · Q9Y4K0

Lysyl oxidase homolog 2

LOXL2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y4K0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LOXL2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.4.3.13
Processing
Precursor
Secondary accessions
B2R5Q0, Q53HV3, Q9BW70, Q9Y5Y8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Basement membraneChromosomeEndoplasmic reticulumExtracellular matrixNucleusSecreted

Ligand

CalciumCopperMetal-binding

Molecular function

Chromatin regulatorOxidoreductaseRepressor

PTM

Disulfide bondGlycoproteinLTQTPQ

Domain

RepeatSignal

Biological process

TranscriptionTranscription regulation

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