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Naptumomab Biosimilar - Research Grade

CAT: 1148-ICH5007-50mgSize: 50 mgDry Ice: NoHazardous: No
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CAT#:1148-ICH5007-50mgSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Naptumomab is a fusion protein consisting of the antigen-binding fragment (Fab) of a monoclonal antibody with the superantigen staphylococcal enterotoxin A (SEA/E-120, "estafenatox"). The Fab binds to 5T4, an antigen expressed by various tumor cells, and the superantigen induces an immune response by activating T lymphocytes.
Specifications
Detects human 5T4. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Naptumomab.
Product Name Alternative
Naptumomab estafenatox, ABR-217620
UniProt
Q13641
Species Reactivity
Human
Target
5T4
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

UniProtKB · Q13641

Trophoblast glycoprotein

TPBG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13641
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TPBG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K555
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Leucine-rich repeatRepeatSignalTransmembraneTransmembrane helix

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