Mouse Anti-Mouse PD-L1 (10F.9G2) Recombinant Antibody (LALAPG)
CAT:
1148-ICH1183LALAPG-10mg
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Mouse PD-L1 (10F.9G2) Recombinant Antibody (LALAPG)
- Background: CD274, also known as B7-H1 and PD-L1, is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes.
- Specifications: Mouse anti-mouse PD-L1 antibody (10F.9G2) is a recombinant antibody where the original rat IgG2b backbone of 10F.9G2 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse CD274
- Product Name Alternative: Programmed cell death 1 ligand 1, Cd274, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
- CAS Number: 9000-83-3
- UniProt: Q9EP73
- Host: Mouse
- Species Reactivity: Mouse
- Target: PD-L1
- Isotype: IgG2a
- Clone: 10F.9G2
- Applications: Flow Cytometry, Blocking, IHC (Frozen), Immunofluorescence, Functional Assays
- Purification Method: This monoclonal antibody was purified using Protein A
- Concentration: 1.0 - 5.0 mg/mL
- Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
- Purity: >95% by SDS-PAGE and HPLC
- Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
- Shipping Conditions: Blue ice
- Storage Conditions: Mouse Anti-mouse PD-L1 antibody (10F.9G2) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
- Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Antigen Distribution: The CD274 antigien is present on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes
- Aggregation: Aggregation level ≤ 5%
- Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
- Isotype Control: https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247