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Flavoxate (hydrochloride)

CAT: 0804-HY-B0549A-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0549A-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flavoxate hydrochloride is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate hydrochloride is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate hydrochloride shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate hydrochloride can be used for the research of overactive bladder (OAB) and lower urinary tract infections[1].
CAS Number
3717-88-2
Product Name Alternative
Rec-7-0040; DW61
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel; mAChR; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Flavoxate-hydrochloride.html
Purity
99.70
Solubility
DMSO : 3.33 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=C2C(C(C(C)=C(C3=CC=CC=C3)O2)=O)=CC=C1)OCCN4CCCCC4.Cl
Molecular Formula
C24H26ClNO4
Molecular Weight
427.92
Precautions
H302, H315, H319, H335
References & Citations
[1]Dansette, P.M., et al. HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins. Exp Toxicol Pathol, 2000. 52 (2) : p. 145-8.|[2]Kimura, Y., et al., Mechanisms of the suppression of the bladder activity by flavoxate. Int J Urol, 1996. 3 (3) : p. 218-27.|[3]Oka, M., et al., Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats. Brain Res, 1996. 727 (1-2) : p. 91-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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