Flavoxate

CAT: 0804-HY-B0549Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-B0549Size:1 Each
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Description
Flavoxate is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate is an antispasmodic agent and muscarinic mAChR antagonist. Flavoxate shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate can be used for the research of overactive bladder (OAB) and lower urinary tract infections[1][2].
CAS Number
[15301-69-6]
Product Name Alternative
Rec-7-0040 (free base) ; DW61 (free base)
UNSPSC
12352005
Target
Calcium Channel; mAChR; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/flavoxate.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2C(C(C(C)=C(C3=CC=CC=C3)O2)=O)=CC=C1)OCCN4CCCCC4
Molecular Formula
C24H25NO4
Molecular Weight
391.46
References & Citations
[1]Arcaniolo D, et al. Flavoxate: present and future. Eur Rev Med Pharmacol Sci. 2015;19 (5) :719-31. |[2]Sugaya K, et al. Intravenous or local injections of flavoxate in the rostral pontine reticular formation inhibit urinary frequency induced by activation of medial frontal lobe neurons in rats. J Urol. 2014 Oct;192 (4) :1278-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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