RFC2 Antibody / Replication factor C subunit 2

RFC2 Antibody / Replication factor C subunit 2

• Description: Replication factor C subunit 2, also called Activator 1 40 kDa subunit (A1 40 kDa subunit) and Replication factor C 40 kDa subunit (RF-C 40 kDa subunit or RFC40), is a protein that in humans is encoded by the RFC2 gene. This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.
• CAS Number: 9007-83-4
• UniProt: P35250
• Host: Rabbit
• Immunogen: E. coli-derived recombinant human protein (amino acids E40-K313) was used as the immunogen for the RFC2 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, IF, FACS, Direct ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the RFC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This RFC2 antibody is available for research use only.