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EphB4 Monoclonal Antibody

CAT: 0965-JOT-MCA0492-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-MCA0492-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
CAS Number
9007-83-4
Synonyms
EPHB4; HTK; MYK1; TYRO11; Ephrin type-B receptor 4; Hepatoma transmembrane kinase; Tyrosine-protein kinase TYRO11
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant extracellular fragment of human EphB4 fused with hIgGFc tag expressed in HEK293 cell line.
Clonality
Monoclonal
Applications
WB, IF, ICC, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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