Recombinant EPHB4 Monoclonal Antibody

• Background:

  EPHB4 together with its cognate ligand/functional ligand EFNB2 they are involved in the regulation of cell adhesion and migration, and play a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.

• Abbreviation:

  EPHB4

• UniProt:

  P54760

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human EPHB4 fragment

• Target:

  MYK; EPHB; TYRO; EPHB4; HFASD; HTK; MYK1; TYRO11

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A214

• Conjugation:

  Unconjugated

• Applications:

  WB; IF; FCM

• Field of Research:

  Cardiovascular; Neuroscience; Stem Cells; Signal Transduction; Cancer

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IF 1:50; FCM 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  108 kDa

• Observed Molecular Weight:

  120 kDa

• Isotype:

  IgG, κ