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TR13C Polyclonal Antibody

CAT: 0965-JOT-AP15104-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15104-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
CAS Number
9007-83-4
Synonyms
Tumor necrosis factor receptor superfamily member 13C ;B-cell-activating factor receptor;BAFF receptor;BAFF-R;BLyS receptor 3;CD antigen CD268
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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