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TBX21 Polyclonal Antibody

CAT: 0965-JOT-AP14805-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14805-01Size:20 µL
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Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
CAS Number
9007-83-4
Synonyms
T-box transcription factor TBX21 ;T-box protein 21;T-cell-specific T-box transcription factor T-bet;Transcription factor TBLYM
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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