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TBX1 Polyclonal Antibody

CAT: 0965-JOT-AP08863-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08863-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11. , where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
CAS Number
9007-83-4
Synonyms
TBX1; T-box transcription factor TBX1; T-box protein 1; Testis-specific T-box protein
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human TBX1. AA range:311-360
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
43133
Antibody Type
Primary antibody
Isotype
IgG