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RFIP5 Polyclonal Antibody

CAT: 0965-JOT-AP13683-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13683-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
disease:Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS), and in the sera from mothers of children with neonatal lupus erythematosus (NLE).,Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).,Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane.,PTM:Phosphorylated on serine and threonine residues.,Contains 1 C2 domain.,subunit:Forms an heterooligomeric complex with RAB11FIP4. Binds NAPG and SSA2. Binds RAB11A that has been activated by GTP binding.,tissue specificity:Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.,
CAS Number
9007-83-4
Synonyms
Rab11 family-interacting protein 5 ;Rab11-FIP5;Gamma-SNAP-associated factor 1;Gaf-1;Phosphoprotein pp75;Rab11-interacting protein Rip11
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 570-650
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG