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PZP Polyclonal Antibody

CAT: 0965-JOT-AP13427-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13427-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.,Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.,subunit:Homotetramer, which consists of two pairs of disulfide-linked chains.,tissue specificity:Plasma. Prominent constituent of late-pregnancy sera.,
CAS Number
9007-83-4
Synonyms
Pregnancy zone protein ;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1301-1350
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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