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PKR Polyclonal Antibody

CAT: 0965-JOT-AP07245-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07245-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for EIF2AK2.
CAS Number
9007-83-4
Synonyms
EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-depe
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human PKR. AA range:413-462
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
62094
Antibody Type
Primary antibody
Isotype
IgG

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