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PKN3 Polyclonal Antibody

CAT: 0965-JOT-AP13131-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP13131-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 protein kinase domain.,Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
CAS Number
9007-83-4
Synonyms
Serine/threonine-protein kinase N3 ;EC 2.7.11.13;Protein kinase PKN-beta;Protein-kinase C-related kinase 3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG