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PEK/PERK Polyclonal Antibody

CAT: 0965-JOT-AP12928-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12928-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
CAS Number
9007-83-4
Synonyms
Eukaryotic translation initiation factor 2-alpha kinase 3 ;EC 2.7.11.1;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK; Eukaryotic translation initiation factor 2-alpha kinase 3; EC 2.7.11.1; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human PEK/PERK Polyclonal
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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