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NR1H2 Polyclonal Antibody

CAT: 0965-JOT-AP12006-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12006-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009
CAS Number
9007-83-4
Synonyms
Oxysterols receptor LXR-beta ;Liver X receptor beta;Nuclear receptor NER;Nuclear receptor subfamily 1 group H member 2;Ubiquitously-expressed nuclear receptor
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG