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Alcaftadine (Standard)

CAT: 0804-HY-17039R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17039R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alcaftadine (Standard) is the analytical standard of Alcaftadine. This product is intended for research and analytical applications. Alcaftadine (R89674) is a histamine H1 receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects[1][2].
CAS Number
147084-10-4
Product Name Alternative
R89674 (Standard)
UNSPSC
12352005
Target
Histamine Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/alcaftadine-standard.html
Smiles
O=CC1=CN=C2N1CCC3=CC=CC=C3/C2=C4CCN(C)CC\4
Molecular Formula
C19H21N3O
Molecular Weight
307.39
References & Citations
[1]Namdar, R. and C. Valdez, Alcaftadine: a topical antihistamine for use in allergic conjunctivitis. Drugs Today (Barc), 2011. 47 (12) : p. 883-90.|[2]Mahvan, T.D., W.A. Buckley, and J.R. Hornecker, Alcaftadine for the prevention of itching associated with allergic conjunctivitis. Ann Pharmacother, 2012. 46 (7-8) : p. 1025-32.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards