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DNMT1 Polyclonal Antibody

CAT: 0965-JOT-AP08573-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP08573-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
DNA ;cytosine-5-methyltransferase 1 ;Dnmt1;EC 2.1.1.37;CXXC-type zinc finger protein 9;DNA methyltransferase HsaI;DNA MTase HsaI;M.HsaI;MCMT
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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