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DAAM1 Polyclonal Antibody

CAT: 0965-JOT-AP15173-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15173-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct
CAS Number
9007-83-4
Synonyms
Disheveled-associated activator of morphogenesis 1; Disheveled-associated activator of morphogenesis 1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide from human protein at AA range: 400-500
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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