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CD1B Polyclonal Antibody

CAT: 0965-JOT-AP07309-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07309-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
CAS Number
9007-83-4
Synonyms
T-cell surface glycoprotein CD1b ;CD antigen CD1b; T-cell surface glycoprotein CD1b; CD antigen CD1b
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide from human protein at AA range: 60-100
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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