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CASR Polyclonal Antibody

CAT: 0965-JOT-AP14684-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14684-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
CAS Number
9007-83-4
Synonyms
Extracellular calcium-sensing receptor; CASR; GPRC2A; PCAR1; Extracellular calcium-sensing receptor; CaSR; Parathyroid cell calcium-sensing receptor; PCaR1
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Synthetic Peptide of CASR
Clonality
Polyclonal
Applications
WB, IHC-p, IF
Stability
-20°C for 1 year
Antibody Type
Primary antibody
Isotype
IgG

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