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ARRS Polyclonal Antibody

CAT: 0965-JOT-AP14333-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14333-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
CAS Number
9007-83-4
Synonyms
S-arrestin ;48 kDa protein;Retinal S-antigen;S-AG;Rod photoreceptor arrestin
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG