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AMGO2 Polyclonal Antibody

CAT: 0965-JOT-AP14198-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14198-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.,Belongs to the immunoglobulin superfamily. AMIGO family.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.,subunit:Binds itself as well as AMIGO1 and AMIGO3.,tissue specificity:Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.,
CAS Number
9007-83-4
Synonyms
Amphoterin-induced protein 2 ;AMIGO-2;Alivin-1;Differentially expressed in gastric adenocarcinomas;DEGA
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 270-350
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG