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ACL6B Polyclonal Antibody

CAT: 0965-JOT-AP14102-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP14102-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold| which is an ATP-binding cleft| as a common feature. The ARPs are involved in diverse cellular processes| including vesicular transport| spindle orientation| nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals| which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin| specifically in the brain. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
Actin-like protein 6B ;53 kDa BRG1-associated factor B;Actin-related protein Baf53b;ArpNalpha;BRG1-associated factor 53B;BAF53B
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG